●It is a rare auto immune disease seen in young female.
●It has grave (Dangerous) prognosis.
●In this disease many organ of body are affected and in 60-70% cases kidney is also involved.
●There is deposition of immune complex at basement membrane, Neutrophils are seen in glomeruli membrane.
●Neutrophils are seen in glomeruli with necrosis and fibrosis.
●The wall of capillary becomes thick which give it wire loop look.
●An inflammatory disease caused when the immune system attacks its own tissues.
●Lupus (SLE) can affect the joints, skin, kidneys, blood cells, brain, heart and lungs.
◆Fatigue
◆Joint pain
◆Rash and fever
12 lupus symptoms and signs
Common lupus complaints and symptoms and signs include
- fatigue or feeling tired,
- low-grade fever,
- loss of appetite,
- joint pain ,
- muscle aches,
- hair loss (alopecia),
- arthritis,
- ulcers of the mouth and nose,
- facial rash ("butterfly rash"),
- unusual sensitivity to sunlight (photosensitivity),
- chest pain caused by inflammation of the lining that surrounds the lungs (pleuritis) and the heart (pericarditis), and
- poor circulation to the fingers and toes with cold exposure (Raynaud's phenomenon)
Laboratory tests:-
-Complete blood count
-Erythrocyte sedimentation rate
-Kidney and liver assessment
-Urinalysis
-Antinuclear antibody (ANA) test
●:-AKSHAY KEWAT
INSTAGRAM PROFILE :-