What Is Blood? Types, Functions & Clinical Importance

What is Blood?

  • Blood is a connective tissue that flows through blood vessels.
  • It helps in transport, protection, and regulation in the body.
  • It is bright red when oxygenated and dark red when deoxygenated.

1. Composition of Blood

Blood = Plasma + Formed Elements (Cells)

Total volume:

  • Adult male: ~5–6 L
  • Adult female: ~4–5 L
  • Blood is ~8% of body weight

A. Plasma (55% of blood)

  • Straw-colored fluid
  • Made up of:

Component

% / Function

Water

90–92% (solvent, transport)

Proteins

6–8%

– Albumin

Maintains osmotic pressure

– Globulin

Immunity

– Fibrinogen

Blood clotting

Electrolytes

Na⁺, K⁺, Cl⁻, HCO₃⁻ – maintain balance

Nutrients

Glucose, AAs, lipids – energy

Hormones

For regulation

Waste Products

Urea, creatinine – excreted by kidneys

Mnemonic: "WE PHWEN"
W – Water
E – Electrolytes
P – Proteins
H – Hormones
W – Waste
E – Enzymes
N – Nutrients


 B. Formed Elements (45% of blood)

Component

Count (approx.)

Function

RBCs

4.5–6 million/μL

O₂ transport (via Hb)

WBCs

4,000–11,000/μL

Defense

Platelets

1.5–4 lakh/μL

Blood clotting

Mnemonic: “RWP = Real White Platelets”

2. Functions of Blood

1. Transport Function

  • O₂ & CO₂ via RBCs
  • Nutrients to cells
  • Hormones to organs
  • Waste to kidneys/lungs

2. Regulatory Function

  • Maintains pH via buffers
  • Maintains temperature (thermoregulation)
  • Maintains fluid–electrolyte balance

3. Protective Function

  • WBCs defend against infection
  • Platelets help in clotting
  • Antibodies in plasma

Mnemonic: “TRP” = Transport, Regulation, Protection

Or:

“Hey! TRy to Protect!”

  • T – Transport
  • R – Regulation
  • P – Protection

3. Specific Gravity of Blood

It is the ratio of the weight of blood to the weight of an equal volume of water.

Component

Specific Gravity

Whole blood (male)

1.050–1.060

Whole blood (female)

1.045–1.055

Plasma

1.025–1.030

RBCs

1.090

Higher protein or cell content = higher specific gravity


Mnemonic to Remember S.G. Order:

“Really Thick People Bleed”
R – RBCs (highest SG)
T – Total blood
P – Plasma
B – Base (water = 1.000)


FAQs – Frequently Asked Questions

Q1. What is the normal volume of blood in an adult?

Ans: About 5–6 L in males, and 4–5 L in females (8% of body weight).

Q2. What are the major components of blood?

Ans:

  1. Plasma (55%)
  2. Formed elements (RBCs, WBCs, Platelets – 45%)

Q3. What is the function of albumin?

Ans: Maintains osmotic pressure of blood and transports substances.

Q4. What is specific gravity and its normal range in blood?

Ans: Specific gravity is the density of blood compared to water.

  • Whole blood: 1.045–1.060

Q5. Why is blood called connective tissue?

Ans: Because it connects all parts of the body by transporting nutrients, oxygen, and waste, and contains cells in an extracellular fluid (plasma).

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