Atrial Septal Defect (ASD): Causes, Symptoms, Diagnosis & Treatment

A hole in the septum between the atria (upper heart chambers), allowing left-to-right shunting of blood.

Most Common in Females (2:1 Female-to-Male Ratio)

Types of ASD:

  1. Ostium Secundum (Most Common) → Defect in the Fossa Ovalis (former Foramen Ovale).
  2. Ostium Primum → Associated with cleft mitral valve.

  Mnemonic: "ASD = Atria’s Septal Defect"


CAUSES OF ASD

Congenital (From Birth) → Failure of normal septum formation.
Genetic SyndromesDown Syndrome (Common in Ostium Primum ASD).

  Mnemonic: "ASD = Atrial Septum Defect"


SYMPTOMS OF ASD

Small ASD (No Symptoms, Found by Chance)
Large ASD (Symptoms Appear in Later Life)

  • Shortness of breath (Dyspnea) on exertion
  • Frequent chest infections in children
  • Palpitations (Atrial Fibrillation in Adults)
  • Heart Failure (Late stage due to pulmonary hypertension)

  Mnemonic: "ASD = Asymptomatic or Slow Dyspnea"


HEART SOUNDS IN ASD

  Wide Fixed Split of S2 → Due to delayed right ventricular emptying.
  Systolic Ejection Murmur (Pulmonary Valve Area) → Due to increased blood flow.
  Diastolic Flow Murmur (Tricuspid Area) → Due to excessive right atrial filling.

  Mnemonic: "A.S.D. Murmurs"

  • Atrial Murmur (Systolic over Pulmonary Valve)
  • Splitting of S2 (Wide & Fixed)
  • Diastolic Murmur (Tricuspid Valve)

COMPLICATIONS OF ASD

Heart Failure (Late)
Pulmonary Hypertension
Eisenmenger’s Syndrome (Shunt Reversal → Cyanosis & Clubbing)
Atrial Fibrillation & Stroke (Due to blood clots)

  Mnemonic: "H-P-E-A" (Complications of ASD)

  • Heart Failure
  • Pulmonary Hypertension
  • Eisenmenger’s Syndrome
  • Arrhythmia (Atrial Fibrillation)

DIAGNOSIS OF ASD

  ECGRight Bundle Branch Block (RBBB), Left Axis Deviation (Primum ASD)
  Chest X-rayLarge Pulmonary Arteries, Enlarged Right Heart
  Echocardiography (ECHO – Best Test!) → Confirms size & location of ASD
  Doppler Color Flow ImagingDetects Left-to-Right Shunt

  Mnemonic: "ECHO-X" (Tests for ASD)

  • ECHO → Best Test
  • Chest X-ray → Heart & Lung Findings
  • Holter Monitor → If Arrhythmia is Suspected
  • Oxygen Check (Pulse Oximetry)

TREATMENT OF ASD

1. SMALL ASD

  No treatment needed! (Most close by age 2-5 years)

2. LARGE ASD (With Symptoms)

  Medications:

  • Diuretics (Furosemide) → Reduce extra fluid
  • Beta-Blockers (If Arrhythmias)

  Surgical Closure (If Pulmonary Flow >1.5:1)

  • Percutaneous Device Closure (For Secundum ASD)
  • Open-heart Surgery (For Primum ASD or Large Defects)

  Mnemonic: "DOP" (Drugs for ASD)

  • Diuretics
  • Oxygen if Needed
  • Percutaneous/Surgical Closure

CONTRAINDICATIONS FOR ASD SURGERY

  • Eisenmenger’s Syndrome (Irreversible Pulmonary Hypertension)
  • Severe Right Heart Failure

  Mnemonic: "Eisenmenger = End of Surgery"


PROGNOSIS OF ASD

  • Small ASD → Excellent (May close on its own)
  • Large ASD → Good if Treated Early
  • Untreated Large ASD → Heart Failure & Stroke Risk

Mnemonic: "ASD = Asymptomatic or Slow Dyspnea"


FINAL REVISION WITH MNEMONICS

  • ASD = "Atria’s Septal Defect"
  • Symptoms = "ASD = Asymptomatic or Slow Dyspnea"
  • Heart Sounds = "A.S.D. Murmurs" (Atrial Murmur, S2 Split, Diastolic Flow Murmur)
  • Complications = "H-P-E-A" (Heart Failure, Pulmonary HTN, Eisenmenger, Arrhythmia)
  • Diagnosis = "ECHO-X" (ECHO, X-ray, Holter, Oxygen Check)
  • Treatment = "DOP" (Diuretics, Oxygen, Percutaneous Closure)
  • Surgery Contraindicated in Eisenmenger's (Mnemonic: "Eisenmenger = End of Surgery")

 

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