Ventricular Septal Defect (VSD): Causes, Symptoms, Diagnosis & Treatment

A hole in the septum between the ventricles (lower heart chambers), allowing blood to flow from left to right.

Types:

  • Small VSDMurmur, but no major symptoms (may close on its own).
  • Large VSDHeart failure, Eisenmenger’s syndrome (serious complications).

  Most Common Congenital Heart Defect! (1 in 500 live births)


CAUSES OF VSD

Congenital (Present from birth) → Due to incomplete septum formation during fetal development.
Acquired (Rarely)Heart attack (MI rupture), Trauma.

Mnemonic: "VSD = Ventricular Septum Defect"


SYMPTOMS OF VSD

Small VSD (Mild or No Symptoms)

  • Loud murmur (Pansystolic) → "Maladie de Roger"
  • Normal growth & development

Large VSD (Severe Symptoms)

  • Heart Failure in Babies (Tachypnea, Sweating, Poor Feeding)
  • Recurrent Chest Infections
  • Cyanosis (if untreated, due to Eisenmenger’s Syndrome)

  Mnemonic: "VSD = Very Small or Dangerous" (Mild vs. Severe Symptoms)


HEART MURMUR IN VSD

  • Pansystolic (Holosystolic) Murmur → Heard best at the left sternal edge
  • Small VSD → Loud Murmur (Because of high-pressure flow)
  • Large VSD → Soft Murmur (Due to equalized pressures)

  Mnemonic: "Small Hole = LOUD, Big Hole = SOFT"


COMPLICATIONS OF VSD

Heart Failure (Excessive blood flow to lungs → overloads heart)
Eisenmenger’s Syndrome (Shunt reversal → Cyanosis, Clubbing)
Pulmonary Hypertension
Endocarditis (Infection in Heart)

  Mnemonic: "HEEP" (VSD Complications)

  • Heart Failure
  • Eisenmenger’s Syndrome
  • Endocarditis
  • Pulmonary Hypertension

DIAGNOSIS OF VSD

  • Chest X-ray → Shows enlarged heart, increased lung blood flow
  • ECGRight & Left Ventricular Hypertrophy (if severe)
  • Echocardiography (ECHO – Best Test!) → Confirms size & location of defect
  • Color DopplerDetects exact shunt flow

  Mnemonic: "ECHO-X" (Tests for VSD)

  • ECHO → Confirms Diagnosis
  • Chest X-ray → Checks Heart Size
  • Holter Monitor → If Arrhythmia is Suspected
  • Oxygen Saturation (Pulse Oximetry)

TREATMENT OF VSD

1. SMALL VSD

  No treatment needed! (Most close by 2-5 years)
  Endocarditis Prophylaxis (Prevent infection)

2. LARGE VSD (With Heart Failure)

  Medications:

  • Diuretics (Furosemide) → Reduce excess fluid
  • Digoxin → Strengthens heart contraction

  Surgery:

  • Indicated if Symptoms Persist (By age 1-2 years)
  • Options:
    • Open-heart surgery (Patch Closure)
    • Catheter-based Closure (Less invasive, for small-moderate defects)

  Mnemonic: "DOP" (Drugs for VSD)

  • Diuretics
  • Oxygen & Digoxin
  • Prophylaxis for Endocarditis

EISENMENGER'S SYNDROME (SEVERE UNTREATED VSD)

  What happens?

  • Left-to-Right Shunt Reverses → Becomes Right-to-Left
  • Cyanosis & Clubbing Develop
  • Pulmonary Hypertension (Irreversible)

  Signs:

  • Blue Skin (Cyanosis)
  • Clubbing of Fingers & Toes
  • Loud P2 Sound on Heart Exam

  Treatment:

  • Heart-Lung Transplant (Only cure!)
  • Avoid Surgery if Eisenmenger’s is Fully Developed

  Mnemonic: "VSD → Eisenmenger = Very Serious Disease"


PROGNOSIS OF VSD

  • Small VSD → Excellent Outcome (Most close by age 5)
  • Large VSD → Good if Treated Early
  • Eisenmenger’s Syndrome → Poor Outcome Without Transplant

  Mnemonic: "VSD = Very Small or Dangerous"


FINAL REVISION WITH MNEMONICS

  • VSD = "Ventricular Septum Defect" (Hole in Ventricles)
  • Symptoms = "VSD = Very Small or Dangerous" (Small = Loud Murmur, Large = Heart Failure)
  • Murmur = "Small Hole = LOUD, Big Hole = SOFT"
  • Complications = "HEEP" (Heart Failure, Eisenmenger, Endocarditis, Pulmonary HTN)
  • Diagnosis = "ECHO-X" (ECHO, X-ray, Holter, Oxygen Check)
  • Treatment = "DOP" (Diuretics, Oxygen/Digoxin, Prophylaxis) 


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