What is the Lymphatic System? Anatomy, Components & Their Roles

1. Introduction

  • The lymphatic system is a part of the circulatory and immune systems.
  • It helps in:
    • Returning excess tissue fluid to the blood
    • Absorption of fats from the intestines
    • Protecting the body from infections
  • It consists of lymph, lymph vessels, lymphatic organs, and tissues.

2. Components of the Lymphatic System

  1. Lymph – the fluid transported
  2. Lymphatic vessels – carry the lymph
  3. Lymph nodes – filter the lymph
  4. Lymphatic organs – like thymus and spleen
  5. Lymphatic tissues – like tonsils, Peyer’s patches

3. Primary and Secondary Lymphatic Organs

A. Primary Lymphatic Organs

  • These are where lymphocytes are produced and mature.
    • Bone marrow: Produces all blood cells including lymphocytes
    • Thymus: T-lymphocytes mature here

B. Secondary Lymphatic Organs

  • These are where lymphocytes get activated and respond to pathogens.
    • Lymph nodes
    • Spleen
    • Tonsils
    • Mucosa-associated lymphoid tissue (MALT)

4. Lymphatic Vessels

  • Thin-walled tubes that carry lymph
  • Found throughout the body, except:
    • Brain, bone marrow, eyeball
  • Types:
    • Afferent vessels – bring lymph to lymph nodes
    • Efferent vessels – carry lymph away from nodes
  • Have valves to ensure one-way flow

5. Lymph

  • Clear, colorless fluid similar to plasma
  • Formed by filtration of plasma into tissues
  • Contains:
    • Water, proteins, fats
    • Lymphocytes (mostly T & B cells)
    • Sometimes bacteria/foreign particles

6. Lymphatic Capillaries

  • Smallest lymph vessels
  • Blind-ended tubes in tissues
  • Found near blood capillaries
  • Highly permeable – absorb fluid, proteins, lipids, and pathogens
  • Unite to form larger lymphatic vessels

7. Lymphatic Tissues

  • Collections of lymphocytes and reticular tissue
  • Found in:
    • Lymph nodes
    • Spleen
    • Tonsils
    • Peyer’s patches
  • Functions:
    • Filter lymph
    • Trap pathogens
    • Help immune response

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