Thoracic Duct Anatomy: Location, Course, and Clinical Importance

1. Introduction

  • The thoracic duct is the largest lymphatic vessel in the body.
  • It drains lymph from the entire body except:
    • Right upper limb
    • Right thorax
    • Right half of head & neck (these are drained by the right lymphatic duct)

2. Length and Course

  • Length: About 45 cm (18 inches)
  • Begins in the abdomen at a sac-like structure called the cisterna chyli.
  • Ascends through the aortic opening of the diaphragm.
  • Travels upward through the posterior mediastinum into the neck.

3. Path and Relations

  • In the thorax (posterior mediastinum):
    • Lies between the azygos vein (right) and descending aorta (left)
    • Behind: esophagus
    • In front of: vertebral column
  • In the neck:
    • Arches laterally at C7 vertebra
    • Crosses left side behind carotid sheath

4. Termination

  • Ends at the junction of:
    • Left subclavian vein
    • Left internal jugular vein
  • This point is called the left venous angle

5. Tributaries

The thoracic duct receives lymph from:

Below the diaphragm:

  • Both lower limbs
  • Pelvis
  • Abdomen (via cisterna chyli)

Above the diaphragm (left side):

  • Left side of thorax
  • Left upper limb
  • Left half of head and neck
  • Left bronchomediastinal trunk

6. Function

  • Drains lymph from ¾ of the body into the bloodstream.
  • Helps in:
    • Returning excess tissue fluid to the venous system
    • Transport of fat from intestines (via chyle)
    • Maintaining fluid balance in the body
    • Immunity, by carrying lymphocytes

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